Laboratory for Converging Technologies (LCT)



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Publications

Wieghaus KA and Botchwey EA. Nanotechnologies for Cardiovascular Tissue Engineering.  In Nanotechnology and Tissue Engineering, the Scaffold.  CT Laurencin and L Nair, eds.  CRC Press/Taylor and Francis.  In press.

Wieghaus KA, Gianchandani EP, Brown ML, Papin JA, Botchwey EA.  Mechanistic exploration of phthalimide neovascular factor 1 using network analysis tools.  Tissue Eng. 2007 Oct;13(10):2561-75. [PubMed | Abstract | PDF]

Petrie C, Tholpady S, Ogle R, Botchwey E.  Proliferative capacity and osteogenic potential of novel dura mater stem cells on poly-lactic-co-glycolic acid. J Biomed Mater Res A. 2007 Aug 9; [Epub ahead of print]. [PubMed | Abstract | Full Text]

Wieghaus KA, Capitosti SM, Anderson CR, Price RJ, Blackman BR, Brown ML, Botchwey EA.  Small molecule inducers of angiogenesis for tissue engineering. Tissue Eng. 2006 Jul;12(7):1903-13. [PubMed | Abstract | PDF]

Laurencin CT, Khan Y, Kofron M, El-Amin S, Botchwey E, Yu X, Cooper JA Jr.  The ABJS Nicolas Andry Award: Tissue engineering of bone and ligament: a 15-year perspective. Clin Orthop Relat Res. 2006 Jun;447:221-36. [PubMed | Abstract | Full Text | PDF]

El-Amin SF, Botchwey E, Tuli R, Kofron MD, Mesfin A, Sethuraman S, Tuan RS, Laurencin CT.  Human osteoblast cells: isolation, characterization, and growth on polymers for musculoskeletal tissue engineering. J Biomed Mater Res A. 2006 Mar 1;76(3):439-49. [PubMed]

Wieghaus KA, Capitosti SM, Brown ML, and Botchwey EA.  Novel angiogenic compounds for targeted drug delivery.  Materials Research Society Symposium Proceedings, Volume 845: Nanoscale Materials Science in Biology and Medicine. December 2004. [Abstract]
 

Yu X, Botchwey EA, Levine EM, Pollack SR, Laurencin CT.  Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11203-8. [PubMed | Abstract | Full Text | PDF]

Botchwey EA, Pollack SR, Levine EM, Johnston ED, Laurencin CT.  Quantitative analysis of three-dimensional fluid flow in rotating bioreactors for tissue engineering. J Biomed Mater Res A. 2004 May 1;69(2):205-15.  [PubMed | Abstract | Full Text | PDF]

Botchwey EA, Dupree MA, Pollack SR, Levine EM, Laurencin CT.  Tissue engineered bone: measurement of nutrient transport in three-dimensional matrices. J Biomed Mater Res A. 2003 Oct 1;67(1):357-67. [PubMed | Abstract | Full Text | PDF]

Botchwey EA, Pollack SR, El-Amin S, Levine EM, Tuan RS, Laurencin CT.  Human osteoblast-like cells in three-dimensional culture with fluid flow. Biorheology. 2003;40(1-3):299-306. [PubMed | Abstract]

Botchwey EA, Pollack SR, Levine EM, Laurencin CT.  Bone tissue engineering in a rotating bioreactor using a microcarrier matrix system. J Biomed Mater Res. 2001 May;55(2):242-53. [PubMed | Abstract | Full Text | PDF]

Laurencin CT, Lipson SJ, Senatus P, Botchwey E, Jones TR, Koris M, Hunter J.  The stenosis ratio: a new tool for the diagnosis of degenerative spinal stenosis. Int J Surg Investig. 1999;1(2):127-31. [PubMed]

Laurencin C, Attawia M, Botchwey E, Warren R, Attia E. Cell-material systems for anterior cruciate ligament regeneration. In Vitro Cell Dev Biol Anim. 1998 Feb;34(2):90-2.

Attawia MA, Uhrich KE, Botchwey E, Langer R, Laurencin CT.  In vitro bone biocompatibility of poly (anhydride-co-imides) containing pyromellitylimidoalanine. J Orthop Res. 1996 May;14(3):445-54. [PubMed | Abstract]

Attawia MA, Uhrich KE, Botchwey E, Fan M, Langer R, Laurencin CT.  Cytotoxicity testing of poly(anhydride-co-imides) for orthopedic applications. J Biomed Mater Res. 1995 Oct;29(10):1233-40. [PubMed]